An animal study revealed that metformin was able to boost T-cell response, a reslut that could potentially revolutionize vaccine strategies.
Diabetes drug revs up effectiveness of vaccines - FierceVaccines
Metformin triggers AMP-activated protein kinase, a key component in energy metabolism that is used in the development of memory T-cells. "When we give metformin, it's like giving the T-cell response a boost," Russell Jones of McGill University in Canada told Reuters.